Research Findings

Incidence Studies - Skin Cancer other than Melanoma

Female Estrogen-Related Factors and Incidence of Basal Cell Carcinoma in a Nationwide US Cohort (2015)
 Basal cell carcinoma incidence was elevated with late age at natural menopause and with any use of hormone replacement therapy in a cohort of U.S. radiologic technologists.
Ambient temperature and risk of first primary basal cell carcinoma: a nationwide United States cohort study (2015)
 Basal cell carcinoma risk was not significantly associated with lifetime summer ambient temperature in U.S. radiologic technologists in analyses adjusted for lifetime ultraviolet radiation, time spent outdoors, body mass index, eye color, and sex.
Occupational ionising radiation and risk of basal cell carcinoma in US radiologic technologists (1983-2005) (2015)
 Basal cell carcinoma incidence in U.S. radiologic technologists was not associated with cumulative occupational radiation dose to head/neck/arms, however BCC risk was elevated for dose received under age 30 and before 1960.
Prescription diuretic use and risk of basal cell carcinoma in the nationwide U.S. Radiologic Technologists cohort (2014)
 Basal cell carcinoma incidence was increased with diuretic use in overweight and obese, but not in normal weight radiologic technologists.
Use of non-steroidal anti-inflammatory drugs and risk of basal cell carcinoma in the United States Radiologic Technologists Study (2012)
 In a follow-up study of 58,213 radiologic technologists who were cancer-free in the mid-1990s, 2,291 developed a first primary BCC. Any use of NSAIDs was not associated with BCC risk after adjustment for age, gender, and estimated lifetime summer sun exposure, and no dose-response patterns were observed. Gender, birth cohort, cigarette smoking, alcohol consumption, sun exposure, occupational radiation exposure, and sun sensitivity factors did not modify the observed associations.
Basal cell carcinoma and anthropometric factors in the U.S. Radiologic Technologists Cohort Study (2012)
 In a study of 2,291 basal cell carcinoma (BCC) cases (486 men, 1,805 women), BCC risk increased significantly with increasing height, and decreased significantly with increasing weight and BMI in both men and women after adjusting for UVR sensitivity factors and exposures.
Nonmelanoma skin cancer in relation to ionizing radiation exposure among U.S. radiologic technologists (2005)
 Investigators examined risks for basal cell carcinoma (BCC) and squamous cell carcinoma (SCC) associated with surrogate measures of occupational exposure to ionizing radiation, and how these risks are influenced by estimated ultraviolet radiation exposure and other factors. Compared to technologists who began working in 1960 or later, risks for BCC, but not SCC, were elevated in those who began working in periods before 1950 when radiation exposures were likely higher. The relationship between BCC and year began working was not influenced by the technologists exposure to ultraviolet radiation but was significantly stronger among those with lighter compared to darker eye or hair color.
Risk of basal cell carcinoma in relation to alcohol intake and smoking (2003)
 Only a few studies have assessed whether smoking cigarettes or drinking alcohol influence the risk of basal cell carcinoma (BCC). We examined the relationship between alcohol intake and smoking in the USRT cohort study by comparing those who drank multiple drinks per week with those who reported no alcohol consumption. Risks for BCC generally rose with increasing alcohol consumption among both women and men. The highest risk was only about 40% in those drinking 7-14 drinks/week. We found no clear association between smoking and BCC.