Research Findings

Incidence Studies - Melanoma

Risk of melanoma in relation to smoking, alcohol intake, and other factors in a large occupational cohort (2003)
 We assessed the possible contribution of smoking, alcohol use, anthropometric characteristics (i.e., weight, height, body mass index (BMI)) and female hormonal factors to melanoma risk. We found that melanoma risk was not associated with height, weight or BMI, nor with age at menarche, menopausal status, use of hormonal replacement therapy, parity, age at first birth or oral contraceptive use. Melanoma risk was elevated with increasing alcohol use. Smoking for long durations compared to never smoking was inversely related to melanoma risk. It is unclear whether the positive relationship with alcohol intake and inverse relationship with smoking for long duration are causal or whether, for example, sun exposure may have contributed to the findings. Additional studies in the USRT cohort will attempt to examine these findings with more detailed information that is being collected.
Risk of melanoma among radiologic technologists in the United States (2003)
 Some studies, but not all, have identified increased risks of melanoma from ionizing radiation exposure. In this study, as in others, we found that melanoma incidence was related to lighter skin tone, blue or green eyes, red or blond hair color, a family history of melanoma, and indicators of sunlight exposure. After adjusting for these factors, we found that technologists who began working before 1950 had about twice the risk of melanoma than others who first worked in 1970 or later, while risks were not increased in technologists who started working in the 1950s or 1960s. Although the risk appeared to be two-fold in the early-workers, the actual number of cases is low. Among the 3,925 men and women technologists who began working before 1950, 15 developed melanoma.