Research Findings


Use of radiopharmaceuticals in diagnostic nuclear medicine in the United States: 1960-2010 (2015)
 Data were collected from nuclear medicine radiology experts and a comprehensive literature review on the use of radiopharmaceuticals and typical administered activities for nuclear medicine procedures performed during 1960-2010 for use in retrospective reconstruction of occupational and personal medical radiation doses.
A New Era of Low-Dose Radiation Epidemiology (2015)
 Findings from recent epidemiologic studies of low-dose radiation-exposed populations based on record-linkage and pooled analyses of prospective cohort studies have provided additional information on radiogenic risks for cancers, especially leukemia, and have questioned previously reported radiation thresholds for cardiovascular disease and cataracts risks.
Historical review of occupational exposures and cancer risks in medical radiation workers (2010)
 A comprehensive review of epidemiological studies of radiologists, radiologic technologists, cardiologists, and others exposed to medical radiation revealed increased risks of leukemia, breast cancer, and skin cancer among early workers (<1950), but limited evidence for excess risks in more recent workers. However, the recent increasing use of high-dose interventional radiation procedures suggests an urgent need for additional follow-up studies with large populations and comprehensive dose assessment to evaluate cancer and other disease trends and ensure adequate worker protections.
Cancer risks among radiologists and radiological technologists: A review of epidemiological studies (2004)
 Radiologists and radiologic technologists were among the earliest occupational groups exposed to ionizing radiation and represent a large segment of the working population exposed to radiation from human-made sources. The authors reviewed epidemiologic data on cancer risks from eight cohorts of over 270,000 radiologists and technologists in various countries. The most consistent finding was increased mortality due to leukemia among early workers employed before 1950, when radiation exposures were high. This, together with an increasing risk of leukemia with increasing duration of work in the early years, provided evidence of an excess risk of leukemia associated with occupational radiation exposure in that period. While findings on several types of solid cancers were less consistent, several studies provided evidence of a radiation effect for breast cancer and skin cancer.