Research Findings

Biodosimetry - Occupational Radiation

Work history and radioprotection practices in relation to cancer incidence and mortality in US radiologic technologists performing nuclear medicine procedures (2018)
 Among 72,755 U.S. radiologic technologists who were cancer-free (other than non-melanoma skin cancer) at completion of the third cohort survey (2003-2005), 22,360 had ever performed nuclear medicine (NM) procedures. Compared to technologists who never performed NM procedures, those who ever worked with NM did not have significantly increased risks for cancer incidence or mortality. There was limited evidence that risks varied by type or frequency of procedures performed, radiation protection practices employed, or other work practices.
Association of chromosome translocation rate with low dose occupational radiation exposures in US radiologic technologists (2014)
 To corroborate the organ-specific occupational radiation dose estimates from our 2013 enhanced dosimetry, we assessed chromosome translocation rates in circulating lymphocytes from 238 radiologic technologists in relation to estimated occupational red bone marrow (RBM) doses. Chromosome translocation frequencies increased statistically significantly with increasing estimated occupational RBM doses. The dose-response relationship was similar using various statistical methods to account for shared and unshared errors and other dose uncertainties.
Retrospective biodosimetry among United States radiologic technologists (2007)
 Measurement of chromosome translocation frequencies in peripheral blood lymphocytes has been used to quantify prior exposure to ionizing radiation. We assessed translocations frequencies in 152 radiologic technologists with a wide-range of estimated occupational doses. Despite uncertainty in the estimates of occupational red bone marrow absorbed doses, we found good general agreement between the doses and translocation frequencies, lending support to the credibility of the dose assessment for this cohort.